The sodium content of a four-tablet dose is 221.5 mg (9.64 mmol). This should be taken into account when a highly restricted salt diet is recommended, e.g. in some cases of congestive cardiac failure and renal impairment. Each four-tablet dose contains 300 mg (7.5 mmol) of calcium. Care needs to be taken in treating patients with hypercalcaemia, nephrocalcinosis and recurrent calcium containing renal calculi. This medicinal product contains aspartame (E951), a source of phenylalanine. May be harmful or people with phenylketonuria. This medicine contains Carmoisine lake (E122). This may cause allergic reactions. If symptoms do not improve after seven days, the clinical situation should be reviewed. Treatment of children younger than 12 years of age is not generally recommended, except on medical advice.